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Midline2 is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 942-942 doi: 10.1007/s11684-021-0876-z

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Progress in systemic therapy for triple-negative breast cancer

Hongnan Mo, Binghe Xu

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 1-10 doi: 10.1007/s11684-020-0741-5

Abstract: Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer with a heterogeneous

Keywords： triple-negative breast cancer     immunotherapy     targeted therapy    

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Midline2 is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer

Lan Wang,Jueheng Wu,Jie Yuan,Xun Zhu,Hongmei Wu,Mengfeng Li

Frontiers of Medicine 2016, Volume 10, Issue 1,   Pages 41-51 doi: 10.1007/s11684-016-0429-z

Abstract: is an ubiquitin-conjugating E2 enzyme linked to tumor progression and a novel interacting partner of breastHowever, the role of MID2 in breast cancer remains unknown.This study investigated the expression, prognostic value, and role of MID2 in breast cancer.cell lines compared with that in normal breast epithelial cells and paired adjacent non-tumor tissueanalysis demonstrated that MID2 was overexpressed in 272 of 284 (95.8%) paraffin-embedded, archived breast

Keywords： breast cancer     MID2     proliferation     overall survival     xenograft    

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How to judge the association of postmenopausal hormone therapy and the risk of breast cancer

Ling XU

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 290-293 doi: 10.1007/s11684-010-0093-7

Abstract: The relevance of postmenopausal hormone therapy (HT) for breast cancer risk has been long debated, althoughThese unanswered questions include: whether HT has a positive impact on breast cancer; whether riskscancer; breast cancer in postmenopausal women using HT usually has better prognosis than that of nonusersHowever, a possible risk of breast cancer associated with long-term HT usage should not be ignored.With respect to prevention of breast cancer, regular evaluation of individual breast cancer susceptibility

Keywords： breast cancer     postmenopausal hormone therapy     unopposed estrogen therapy     combined estrogen-progestin therapy    

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Metabolism and immunity in breast cancer

Deyu Zhang, Xiaojie Xu, Qinong Ye

Frontiers of Medicine 2021, Volume 15, Issue 2,   Pages 178-207 doi: 10.1007/s11684-020-0793-6

Abstract: Breast cancer is one of the most common malignancies that seriously threaten women’s health.In the process of the malignant transformation of breast cancer, metabolic reprogramming and immune evasionBreast cancer cells generate energy through increased glucose metabolism.For tumor-associated immunity, poor immunogenicity and heightened immunosuppression cause breast cancerinvestigated, and the genes involved in these processes are used as clinical therapeutic targets for breast

Keywords： breast cancer     metabolism     immunity     cancer stem cells    

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Meta-analysis of the risk factors of breast cancer concerning reproductive factors and oral contraceptive

Qiong DAI MD, Bei LIU MD, Yukai DU MM,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 452-458 doi: 10.1007/s11684-009-0080-z

Abstract: studies that addressed whether reproductive factors and oral contraceptive use were associated with breast#8220;*”: summary OR was adjusted; 95% CI, 1.24―3.62) were correlated with the increase in breast(OR, 0.76; 95% CI, 0.64―0.90) indicated no association with breast cancer risk.Menopausal age >50yr and oral contraceptive use are positively correlated with an increase in breastcancer risk while breast-feeding and number of full-term pregnancies ≥1 are protective factors

Keywords： meta-analysis     breast cancer     risk factors     reproductive factors     oral contraceptive use    

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Expression of PC-cell-derived growth factor in breast cancer

Haiping SONG MD, Lan SHI MD, Chunping LIU MD, Tao HUANG MD,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 426-430 doi: 10.1007/s11684-009-0085-7

Abstract: This study is mainly aimed at evaluating the expression of PC-cell-derived growth factor (PCDGF) in breastcancer and breast adenofibroma, and to compare with other commonly used clinical pathological indices, then to investigate the diagnostic and targeted therapeutic purpose of PCDGF in breast cancer tissueWe found that PCDGF was expressed in most breast cancer tissue, but was not in breast adenofibroma tissuetarget of therapy for breast cancer.

Keywords： PC-cell-derived growth factor     breast neoplasms     clinical markers    

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A case of primary neuroendocrine breast carcinoma that responded to neo-adjuvant chemotherapy

Xiaolong Wei,Chunfa Chen,Didi Xi,Jinwen Bai,Wenhe Huang,Luoxiang Rong,Mingyao Wu,Guojun Zhang

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 112-116 doi: 10.1007/s11684-014-0345-z

Abstract:

Primary neuroendocrine breast carcinoma (NEBC) is a very rare type of breast cancer.In this study, a 43-year-old woman with a large mass of 8.3 cm × 2.9 cm in her right breast was

Keywords： neuroendocrine carcinoma     neo-adjuvant therapy     breast    

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frequency of alternative splicing variants of the oncogene in neuroendocrine tumors of the pancreas and breast

Frontiers of Medicine   Pages 907-923 doi: 10.1007/s11684-023-1009-7

Abstract: We further tested FAK splicing variants in breast neuroendocrine carcinoma (BrNECs), and found>6/7 was positive in 14 (93.3%) of 15 BrNECs but 0 in 23 non-NEC breastprotein 4 (SRRM4) was overexpressed in FAK6/7-positive pancreatic tumors and breast

Keywords： FAK6/7     SRRM4     neuroendocrine neoplasms     pancreas     breast    

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Production of pectic extracts from sugar beet pulp with antiproliferative activity on a breast cancer

Jacqueline CONCHA, Caroline WEINSTEIN, María Elvira Zú?IGA

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 4,   Pages 482-489 doi: 10.1007/s11705-013-1342-5

Abstract: decisive in their capacity to induce apoptosis on several cancer cell lines like colon, prostate and breastThe pectic extract was examined for its antiproliferative activity on the MCF-7 breast cancer cell line

Keywords： pectic extracts     antiproliferative activity     breast cancer     enzymatic treatment    

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A comprehensive information database (CID) of breast cancer patients in China

Shuai Li, Li Fu

Frontiers of Medicine 2012, Volume 6, Issue 2,   Pages 212-216 doi: 10.1007/s11684-012-0185-7

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Decitabine induces -mediated immune responses in p53-mutated triple-negative breast cancer: a clinical

Frontiers of Medicine doi: 10.1007/s11684-023-1016-8

Abstract: Here, we reposition decitabine for triple-negative breast cancer (TNBC), a subtype with frequent p53

Keywords： p53 mutation     triple-negative breast cancer     decitabine     DNMT1     IRF7     innate immune response    

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Association of SIPA1 545 C>T polymorphism with survival in Chinese women with metastatic breast cancer

Renling Pei, Ye Xu, Yan Wei, Tao Ouyang, Jinfeng Li, Tianfeng Wang, Zhaoqing Fan, Tie Fan, Benyao Lin, Yuntao Xie

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 138-142 doi: 10.1007/s11684-013-0247-5

Abstract: SIPA1 545 C>T polymorphism was associated with overall survival in patients with metastatic breastIn this study, SIPA1 545 C>T polymorphism was detected in 185 metastatic breast cancer patients;545 C>T polymorphism was significantly associated with survival in 185 patients with metastatic breastOur findings indicate that metastatic breast cancer patients with SIPA1 545 T/T genotype have

Keywords： SIPA1     polymorphism     metastatic breast cancer     survival    

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Function of Slit/Robo signaling in breast cancer

Feng Gu,Yongjie Ma,Jiao Zhang,Fengxia Qin,Li Fu

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 431-436 doi: 10.1007/s11684-015-0416-9

Abstract: The Slit/Robo signaling pathway is reportedly involved in breast cancer development and metastasis.PI3K/Akt signaling pathways or by altering β-catenin/E-cadherin-mediated cell-cell adhesion in breastloss of Slit proteins or their Robo receptors upregulates the CXCL12/CXCR4 signaling axis in human breastIn addition, this pathway regulates the distant migration of breast cancer cells not only by mediatingThis review includes recent studies on the functions of Slit/Robo signaling in breast cancer and its

Keywords： Slit/Robo     hypermethylation     β-catenin     CXCL12/CXCR4     migration    

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Soy food consumption in relation to breast cancer modified by menopause status

YANG Rong, ZHANG Bin, YANG Shaoping, ZHANG Dan, DU Yukai

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 348-351 doi: 10.1007/s11684-008-0066-2

Abstract: The mortality of breast cancer in Wuhan city is increasing, according to the statistics of recent yearsThis case control study was aimed to provide data for alimentary therapeutics for breast carcinomas.indicate that intake of soy foods more than 5 times per week was associated with a decreased risk of breastOur results indicate that alimentary therapeutics for breast cancer can be adjusted by status of menopause

Keywords： development     control     lifestyle     consumption     information    

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Title Author Date Type Operation

Midline2 is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer

Journal Article

Progress in systemic therapy for triple-negative breast cancer

Hongnan Mo, Binghe Xu

Journal Article

Midline2 is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer

Lan Wang,Jueheng Wu,Jie Yuan,Xun Zhu,Hongmei Wu,Mengfeng Li

Journal Article

How to judge the association of postmenopausal hormone therapy and the risk of breast cancer

Ling XU

Journal Article

Metabolism and immunity in breast cancer

Deyu Zhang, Xiaojie Xu, Qinong Ye

Journal Article

Meta-analysis of the risk factors of breast cancer concerning reproductive factors and oral contraceptive

Qiong DAI MD, Bei LIU MD, Yukai DU MM,

Journal Article

Expression of PC-cell-derived growth factor in breast cancer

Haiping SONG MD, Lan SHI MD, Chunping LIU MD, Tao HUANG MD,

Journal Article

A case of primary neuroendocrine breast carcinoma that responded to neo-adjuvant chemotherapy

Xiaolong Wei,Chunfa Chen,Didi Xi,Jinwen Bai,Wenhe Huang,Luoxiang Rong,Mingyao Wu,Guojun Zhang

Journal Article

frequency of alternative splicing variants of the oncogene in neuroendocrine tumors of the pancreas and breast

Journal Article

Production of pectic extracts from sugar beet pulp with antiproliferative activity on a breast cancer

Jacqueline CONCHA, Caroline WEINSTEIN, María Elvira Zú?IGA

Journal Article

A comprehensive information database (CID) of breast cancer patients in China

Shuai Li, Li Fu

Journal Article

Decitabine induces -mediated immune responses in p53-mutated triple-negative breast cancer: a clinical

Journal Article

Association of SIPA1 545 C>T polymorphism with survival in Chinese women with metastatic breast cancer

Renling Pei, Ye Xu, Yan Wei, Tao Ouyang, Jinfeng Li, Tianfeng Wang, Zhaoqing Fan, Tie Fan, Benyao Lin, Yuntao Xie

Journal Article

Function of Slit/Robo signaling in breast cancer

Feng Gu,Yongjie Ma,Jiao Zhang,Fengxia Qin,Li Fu

Journal Article

Soy food consumption in relation to breast cancer modified by menopause status

YANG Rong, ZHANG Bin, YANG Shaoping, ZHANG Dan, DU Yukai

Journal Article